Clinical Progression Scale-Pediatrics: A Potential Metric of Respiratory Syncytial Virus Severity and Progression in Children

• 2025

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• Gabriella Ess; Christina Rostad
PMID: 39792607DOI: https://doi.org/10.1093/infdis/jiaf019

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This editorial comments on a study titled "Assessing Clinical Improvement of Infants Hospitalized for Respiratory Syncytial Virus–Related Critical Illness" by Leland et al. 2025. It found that infants under 3 months old and premature infants may not clinically improve from RSV-related lower respiratory disease, despite available prevention products. Toddlers and young children are still at risk of severe RSV. There is a need for better RSV prevention and treatment in these age groups. The CPS-Ped score shows promise for future studies and trials but requires further validation.

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Tags

Focus Area: Infectious Disease

Audience: Physicians

Emergency Management Stage: Preparedness (Prevention / Protection)

Collection: Nirsevimab Library

Keywords: Bronchiolitis; Child; Child, Preschool; Infant; Pediatrics; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Respiratory Tract Diseases; Severity of Illness Index; Respiratory Syncytial Virus, Human; Disease Progression; Infant, Premature

Institutions: Emory University; Children's Healthcare of Atlanta

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