Respiratory Syncytial Virus Disease Burden and Nirsevimab Effectiveness in Young Children From 2023-2024

• 2024

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• Heidi Moline; Ariana Toepfer; Ayzsa Tannis; Geoffrey Weinberg; Mary Staat; Natasha Halasa
PMID: 39652359DOI: https://dx.doi.org/10.1001/jamapediatrics.2024.5572

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About

This study looks at the impact of respiratory syncytial virus (RSV) in young children during the 2023-2024 season. It describes how two new RSV prevention products, nirsevimab and Pfizer's maternal vaccine, were used to protect infants. The study compares RSV cases from 2017-2020 with those in 2023-2024 and finds similar hospitalization rates. Nirsevimab was found to be highly effective against RSV-related illnesses and hospitalizations. The research highlights the need for more widespread use of these prevention methods to reduce illness in children under five years old.

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Tags

Focus Area: Infectious Disease

Audience: Physicians

Emergency Management Stage: Preparedness (Prevention / Protection)

Bundles: Nirsevimab Library

Keywords: Antibodies, Monoclonal; Child, Preschool; Infant; Prospective Studies; Respiratory Syncytial Virus Infections; Respiratory Tract Infections

Institutions: Centers for Disease Control and Prevention (CDC); U.S. Public Health Service; University of Rochester; University of Cincinnati; Cincinnati Children's Hospital Medical Center; Vanderbilt University; Texas Children's Hospital; Baylor College of Medicine; University of Washington; University of Pittsburgh; Children's Mercy Kansas City

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