Estimated Impact of Nirsevimab on the Incidence of Respiratory Syncytial Virus Infections Requiring Hospital Admission in Children <1 Year, Weeks 40, 2023, to 8, 2024, Spain

• 2024

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• Clara Mazagatos; Jacobo Mendioroz; Mercedes Rumayor; Virtudes Garcia; Virginia Alvarez Rio; Ana Delia Cebollada Gracia
PMID: 38716791DOI: https://dx.doi.org/10.1111/irv.13294

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This article discusses the impact of administering nirsevimab to children in Spain to prevent respiratory syncytial virus (RSV) infections requiring hospitalization. Data from the sentinel surveillance system show a significant reduction (74%-75%) in RSV hospitalizations in children under 1 year. The recommendation for nirsevimab administration, starting in October 2023, led to between 9364 and 9875 averted RSV hospitalizations during the study period. The study highlights the effectiveness of nirsevimab in real-world conditions and its potential to reduce the burden of RSV infections in young children.

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Tags

Focus Area: Infectious Disease

Audience: Physicians

Emergency Management Stage: Preparedness (Prevention / Protection)

Bundles: Nirsevimab Library

Keywords: Antiviral Agents; Epidemiology; Hospitalization; Incidence; Infant; Infant, Newborn; Respiratory Syncytial Virus Infections; Spain; Respiratory Syncytial Virus, Human; Sentinel Surveillance; Antibodies, Monoclonal, Humanized

Institutions: Institute of Health Carlos III (ISCIII); CIBER of Epidemiology and Public Health (CIBERESP); Government of Catalonia; Comunidad de Madrid; Junta de Andalucia; Junta de Castillo y Leon

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