Preventing Respiratory Syncytial Virus (RSV) Disease in Children

• 2021

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• Ruth Karron
PMID: 33986169DOI: https://dx.doi.org/10.1126/science.abf9571

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About

This brief perspective article discusses the progress and promising strategies for RSV immunization to combat the significant burden of RSV infection in young children globally. Highlighting the urgent need to reduce child mortality and morbidity associated with RSV, the text explores the development of RSV vaccines and monoclonal antibodies as potential preventive measures. Through decades of research, the article sheds light on the spectrum of RSV disease, including pneumonia, bronchiolitis, otitis media, and apnea in infants. With ongoing advancements in vaccine and antibody development, there is hope for effective prevention of RSV-related illnesses.

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Tags

Focus Area: Infectious Disease

Audiences: Physicians; Public Health Professionals

Emergency Management Stage: Preparedness (Prevention / Protection)

Bundles: Nirsevimab Library

Keywords: Antibodies, Viral; Clinical Trials as Topic; Immunity, Active; Immunity, Maternally-Acquired; Immunization, Passive; Infant; Pregnancy; Public Health; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Respiratory Tract Infections; Viral Fusion Proteins; Immunoglobulins, Intravenous; Antibodies, Neutralizing; Respiratory Syncytial Virus Vaccines; Antibodies, Monoclonal, Humanized

Institutions: Johns Hopkins University

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