Challenges in Maximizing Impacts of Preventive Strategies Against Respiratory Syncytial Virus (RSV) Disease in Young Children

• 2022

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• Zhe Zheng
PMID: 35782467

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This article discusses the challenges and advancements in preventive strategies against Respiratory Syncytial Virus (RSV) disease in young children. RSV is a common cause of lower respiratory tract illness in infants and children, leading to significant morbidity and mortality globally. The article highlights the importance of effective RSV vaccines and immune-prophylaxis, focusing on three major preventive strategies: RSV F-protein-based vaccines for pregnant women, extended half-life monoclonal antibodies for neonates, and live-attenuated vaccines for infants. It also addresses the remaining questions in the development and implementation of RSV preventive measures, emphasizing the need for further research and collaboration to maximize vaccine impacts.

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Tags

Focus Area: Infectious Disease

Audience: Physicians

Emergency Management Stage: Preparedness (Prevention / Protection)

Bundles: Nirsevimab Library

Keywords: Aged; Antibodies, Monoclonal; Child; Child, Preschool; Infant; Infant, Newborn; Pregnancy; Pregnant Women; Respiratory Syncytial Virus Infections; Vaccination; Respiratory Syncytial Virus, Human; Respiratory Syncytial Virus Vaccines

Institutions: Yale University

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