Monoclonal Antibodies for Prophylaxis and Treatment of Respiratory Viral Infections

• 2022

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• Jim Boonyaratanakornkit; Michael Boeckh; Alpana Waghmare
PMID: 35849517DOI: https://dx.doi.org/10.1097/QCO.0000000000000846

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About

This article discusses the use of monoclonal antibodies (mAbs) to prevent and treat respiratory viral infections, especially in people with weak immune systems. It describes how mAbs have been developed quickly during the COVID-19 pandemic. Some new mAbs have been approved for early COVID-19 treatment but faced challenges due to virus variants. The article highlights ways to improve mAb effectiveness, like extending their lifespan in the body. It also mentions that more mAbs are being developed for viruses like SARS-CoV-2 and RSV, expecting continued growth in available treatments.

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Tags

Focus Area: Infectious Disease

Audience: Physicians

Emergency Management Stage: Preparedness (Prevention / Protection)

Bundles: Nirsevimab Library

Keywords: Antibodies, Monoclonal; Antibodies, Viral; Respiratory Syncytial Virus Infections; Respiratory Tract Infections; Viruses; Pandemics; COVID-19; SARS-CoV-2

Institutions: Fred Hutchinson Cancer Center; University of Washington; Seattle Children's Hospital

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