Cost-Effectiveness Analysis of Nirsevimab and RSVpreF Vaccine Prevention Strategies for Respiratory Syncytial Virus Disease in Infants: A Canadian Immunisation Research Network (CIRN) Study

• 2023

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• Affan Shoukat; Elaheh Abdollahi; Alison Galvani; Scott Halperin; Joanne Langley; Seyed Moghadas
DOI: https://dx.doi.org/10.1101/2023.07.14.23292675

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About

This study looks at the cost-effectiveness of two strategies to prevent RSV disease in infants in Canada. It describes using nirsevimab, a long-acting antibody, for all newborns and combining it with RSVpreF, a vaccine for pregnant women. The research finds that both methods can be cost-effective and reduce infant deaths from RSV. Using both strategies together could save money while providing similar protection as using nirsevimab alone. The study was supported by Canadian health organizations and followed ethical guidelines for research involving participants.

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Tags

Focus Area: Infectious Disease

Audience: Physicians

Emergency Management Stage: Preparedness (Prevention / Protection)

Bundles: Nirsevimab Library

Keywords: Cost-Benefit Analysis; Infant, Newborn; Respiratory Syncytial Virus Infections; Vaccines, Synthetic; Immunization Programs; Antibodies, Monoclonal, Humanized

Institutions: York University; Yale University; Dalhousie University

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