Does Nirsevimab Prevent Lower Respiratory Infections Caused by Respiratory Syncytial Virus?

• 2024

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• Kelsey Sullivan; Brynne Sullivan
PMID: 38637681DOI: https://dx.doi.org/10.1038/s41372-024-01970-y

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This study examines nirsevimab, a monoclonal antibody that helps prevent respiratory syncytial virus (RSV) infections in infants. It found that one injection of nirsevimab significantly reduced RSV-related lower respiratory tract infections compared to a placebo. It was effective for up to 150 days and had a good safety profile. The FDA approved it for use in newborns and infants during their first RSV season, as well as children up to 24 months who are at risk of severe RSV disease. Nirsevimab is expected to reduce the burden of RSV among young children significantly.

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Tags

Focus Area: Infectious Disease

Audiences: Nurses; Physicians; Public Health Professionals

Emergency Management Stage: Preparedness (Prevention / Protection)

Bundles: Nirsevimab Library

Keywords: Antiviral Agents; Infant; Infant, Newborn; Respiratory Syncytial Virus Infections; Respiratory Tract Infections; Premature Birth; Antibodies, Monoclonal, Humanized

Institutions: University of Virginia

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