Impact of Universal Immunization Program With Monoclonal Antibody Nirsevimab on Reducing the Burden of Serious Bronchiolitis That Need Pediatric Intensive Care

• 2024

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• Carme Alejandre; Daniel Penela-Sánchez; Judit Alsina; Marta Agüera; Aleix Soler; Sara Moussalam
PMID: 38910199DOI: https://dx.doi.org/10.1007/s00431-024-05634-z

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About

This study in Catalonia, Spain analyzed the effects of immunizing children with nirsevimab on bronchiolitis cases in pediatric intensive care units (PICU). The research compared pre- and post-nirsevimab periods, showing a significant decrease in PICU admissions for bronchiolitis, shorter hospital stays, and older age at admission post-nirsevimab implementation. This suggests that nirsevimab plays a crucial role in reducing RSV bronchiolitis cases in hospitals.

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Tags

Focus Area: Infectious Disease

Audiences: Nurses; Physicians; Public Health Professionals

Emergency Management Stage: Preparedness (Prevention / Protection)

Bundles: Nirsevimab Library

Keywords: Antiviral Agents; Bronchiolitis; Hospitalization; Infant; Infant, Newborn; Intensive Care Units, Pediatric; Respiratory Syncytial Virus Infections; Spain; Immunization Programs; Antibodies, Monoclonal, Humanized

Institutions: Hospital Sant Joan de Déu Barcelona; University of Barcelona

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