Nirsevimab: Alleviating the Burden Of RSV Morbidity in Young Children

• 2024

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• Marcus Wing Choy Loe; Helen Soenong; Evelyn Lee; Jean Li-Kim-Moy; Phoebe Williams; Kee Thai Yeo
PMID: 39150043DOI: https://doi.org/10.1111/jpc.16643

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This article reviews the real-world data that supports the effectiveness of nirsevimab, a monoclonal antibody that helps protect young children from RSV. Studies have demonstrated significant reductions in RSV-related hospitalizations with nirsevimab treatment. Strategies focus on seasonal administration for infants. While nirsevimab offers public health benefits, economic factors and logistics must be considered for its adoption. While promising, it needs careful planning for widespread use in different countries due to costs and logistics.

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Tags

Focus Area: Infectious Disease

Audiences: Nurses; Physicians; Public Health Professionals

Emergency Management Stages: Response; Preparedness (Prevention / Protection)

Bundles: Nirsevimab Library

Keywords: Antiviral Agents; Child, Preschool; Cost-Benefit Analysis; Hospitalization; Infant; Infant, Newborn; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Immunization Programs; Antibodies, Monoclonal, Humanized

Institutions: Duke-NUS Medical School; KK Women's & Children's Hospital; University of New South Wales; Macquarie University; National Centre for Immunisation Research and Surveillance (NCIRS)

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