Cost-Effectiveness of Nirsevimab for Respiratory Syncytial Virus in Infants and Young Children

• 2024

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• David Hutton; Lisa Prosser; Angela Rose; Kerra Mercon; Ismael Ortega-Sanchez; Andrew Leidner
PMID: 39582316DOI: https://dx.doi.org/10.1542/peds.2024-066461#

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This study evaluated the cost-effectiveness of using nirsevimab to prevent respiratory syncytial virus (RSV) in infants and high-risk children. By analyzing healthcare data, it was estimated that nirsevimab could prevent many outpatient visits, emergency department visits, and hospitalizations. The cost per quality-adjusted life year (QALY) saved was found to be $153,517 for infants in their first RSV season and $308,468 for high-risk children in their second season. Overall, nirsevimab was considered cost-effective, especially for high-risk individuals with increased RSV-related risks and costs.

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Tags

Focus Area: Infectious Disease

Audiences: Nurses; Physicians

Emergency Management Stage: Preparedness (Prevention / Protection)

Bundles: Nirsevimab Library

Keywords: Child; Cost-Benefit Analysis; Infant; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Quality-Adjusted Life Years; Health Care Costs; Immunization Programs; Antibodies, Monoclonal, Humanized

Institutions: University of Michigan; Centers for Disease Control and Prevention (CDC); U.S. Public Health Service

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