Approaches to the Prevention and Treatment of Respiratory Syncytial Virus Infection in Children: Rationale and Progress to Date

• 2024

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• Charl Verwey; Ziyaad Dangor; Shabir Madhi
PMID: 38032456DOI: https://dx.doi.org/10.1007/s40272-023-00606-6

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This article discusses recent research around respiratory syncytial virus (RSV), which is a common cause of lower respiratory tract infection in children, leading to long-term lung issues. Treatment mainly involves supportive care like oxygen therapy. Preventative measures include a monoclonal antibody called Palivizumab and new strategies like vaccines and long-acting antibodies. Recent advancements include nirsevimab, a long-lasting antibody, and a vaccine for pregnant women to protect their infants. Ongoing research is focused on improving prevention and treatment options for RSV infections in children.

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Tags

Focus Area: Infectious Disease

Audiences: Nurses; Physicians

Emergency Management Stages: Response; Preparedness (Prevention / Protection)

Bundles: Nirsevimab Library

Keywords: Child; Immunization, Passive; Infant; Pregnant Women; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Vaccines; Palivizumab; Antibodies, Monoclonal, Humanized

Institutions: University of the Witwatersrand

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