Clade I Monkeypox Outbreak Originating in Central Africa

• 2025

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This webpage details the Clade I mpox outbreak originating in Central Africa, particularly the Democratic Republic of the Congo (DRC), which has reported over 27,000 suspected cases and 1,300 deaths since January 2023. Clade I mpox is more severe than Clade II and is endemic in DRC. The outbreak has spread to neighboring countries, prompting the WHO to declare it a Public Health Emergency of International Concern (PHEIC) on August 14, 2024. The page also covers the spread, prevention, and response efforts in affected regions, including the role of the CDC and other international agencies.

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Tags

Focus Area: Infectious Disease

Audiences: EMS Clinicians; Nurses; Physicians; Public Health Professionals

Emergency Management Stage: Preparedness (Prevention / Protection)

Keywords: Disease Outbreaks; Epidemiology; Monkeypox virus; Vaccination; Democratic Republic of the Congo; Disease Transmission, Infectious; Mpox (monkeypox)

Institutions: Centers for Disease Control and Prevention (CDC)

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The information provided on this website is for educational purposes only. It does not substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

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