Pediatric Sepsis Diagnosis, Management, and Sub-phenotypes

• 2024

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• Scott Weiss; Julie Fitzgerald
PMID: 38084084DOI: https://doi.org/10.1542/peds.2023-062967

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About

This article discusses the challenges of diagnosing and treating sepsis in children, highlighting that sepsis causes many deaths and health issues worldwide. It emphasizes the need for updated definitions and diagnostic criteria, as well as early recognition using automated tools. Key treatments include antibiotics, fluids, and medications to support blood pressure. Research is ongoing to improve treatment strategies, especially for severe cases with multiple organ problems. The goal is to treat more children at risk without overusing antibiotics or causing unnecessary hospital stays.

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Tags

Focus Areas: Everyday Emergency; Infectious Disease

Audience: Physicians

Emergency Management Stages: Response; Preparedness (Prevention / Protection)

Keywords: Biomarkers; Diagnosis; Pediatrics; Phenotype; Quality of Life; Shock, Septic; Sepsis; Anti-Bacterial Agents

Institutions: Nemours Children's Health; Thomas Jefferson University; University of Pennsylvania; Children's Hospital of Philadelphia

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